Genetic analysis to prevent warfarin complications.

نویسندگان

  • Giuseppe Lippi
  • Gian Luca Salvagno
  • Gian Cesare Guidi
چکیده

sleepy drivers (including those with untreated sleep apnea) must be reported to the relevant motor vehicle licensing authority in some provinces. Such reports have the potential to limit an older person’s independence because, as pointed out by Wolkove and colleagues, there is marked variability within Canada in the coverage for continuous positive airway pressure devices, the treatment of choice for obstructive sleep apnea. Astonishingly, some provinces do not cover this therapy at all. Another problem facing Canadian patients with sleep disorders is the variability between provinces in the time patients have to wait for sleep testing. In several provinces patients must wait much longer for testing than recommended by the Canadian Thoracic Society Sleep Disordered Breathing Committee. This places these patients at increased medical risk; the increased risk that they will be involved in an automobile accident may also endanger the public.

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The Contribution of VKORC1 and CYP2C9 Genetic Polymorphisms and Patients’ Demographic Characteristics with Warfarin Maintenance Doses: A Suggested Warfarin Dosing Algorithm

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عنوان ژورنال:
  • CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

دوره 177 4  شماره 

صفحات  -

تاریخ انتشار 2007